Altitude and the human pulmonary circulation.

Pulmonary arterial hypertension in man at altitude was first demonstrated by Rotta, Canepa. Hurtado. Velasquez & Chavez (1956). One year before Vega (1955) had published the first comprehensive clinical account of high altitude pulmonary oedema. Since the mid-sixties. interest in both pulmonary hypertension and pulmonary oedema at altitude has continued to generate a great deal of clinical and experimental research.